In situ molecular pathology and co-expression analyses

This new laboratory reference manual will explain, in easy-to-understand language, simplified ways to understand and perform in situ hybridization and immunohistochemistry tests. The book will also focus much attention on straightforward protocols used to simultaneously detect two or more proteins/n...

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Bibliographic Details
Main Author: Nuovo, Gerard J.
Format: Book
Language:English
Published: Amsterdam ; Boston Elsevier c2013
Subjects:
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Call Number :med QU 58 .N86 2013

MARC

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100 1 |a Nuovo, Gerard J. 
245 1 0 |a In situ molecular pathology and co-expression analyses  |c Gerard J. Nuovo 
260 |a Amsterdam ;  |a Boston  |b Elsevier  |c c2013 
300 |a vii, 289 p.  |b ill. (some col.)  |c 28 cm 
504 |a Includes bibliographical references and index 
520 |a This new laboratory reference manual will explain, in easy-to-understand language, simplified ways to understand and perform in situ hybridization and immunohistochemistry tests. The book will also focus much attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols and regimens for troubleshooting to maximize the use of these platforms. Practicing molecular pathologists, clinical chemists, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry, especially with computer based co-expression analyses, offer a large advantage to researchers competing for federal moneys or private grants. Includes over 200 easy-to-follow experimental protocolsFeatures chapter-ending summaries of "Key Points to Remember" to bring beginners up to speed with any seasoned veteran in the field. Offers two chapters written by industry leaders in the fields of in situ hybridization, immunohistochemistry, and computer software for co-expression analyses. 
592 |a PI 00132  |b 29/08/2014  |c RM 412.08  |h RIMA 
650 2 |a In Situ Hybridization 
650 2 |a Immunohistochemistry  |x methods 
650 2 |a Gene Expression Profiling  |x methods 
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