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Down syndrome from understanding the neurobiology to therapy

Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of th...

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Bibliographic Details
Other Authors: Dierssen, Mara, Torre, Rafael de la
Format: Book
Language:English
Published: Amsterdam ; Boston Elsevier 2012.
Edition:1st ed.
Series:Progress in brain research ; v. 197
Subjects:
Down Syndrome > genetics
Down Syndrome > therapy
Neurons > pathology
Brain > pathology
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