Stem cells and bone tissue

Preface Bone diseases, characterised by either fractures, stunting, loss of mineral composition or strength, are important causes of morbidity and mortality. For example worldwide there are 9 million new cases of fractures due to osteoporosis annually and this has increased by 50% in the past 2 deca...

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Other Authors: Rajendram, Rajkumar (Editor), Preedy, Victor R. (Editor), Patel, Vinood B. (Editor)
Format: Book
Language:English
Published: Boca Raton, FL CRC Press 2013
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264 1 |a Boca Raton, FL  |b CRC Press  |c 2013 
300 |a ix, 412 pages  |b illustrations  |c 24 cm 
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505 0 |a Endothelial progenitor cell-based therapy for orthopaedic regenerative medicine -- Transplanted bone marrow stromal cells and bone tissue regeneration -- Isolation and purification methods for mesenchymal stem cells -- The human nose offers a new stem cell source for bone injuries -- Multipotential mesenchymal stromal/stem cells in skeletal tissue repair -- Adipose-derived stem cells (ASCs) and bone repair: an overview in regenerative medicine -- The modulation of skeletal stem cell function through nanoscale topography -- Myostatin (GDF-8) signaling in progenitor cells and applications to bone repair -- c-Jun-centered regulatory network of signalling pathways in bone stem cells and applications to bone repair -- Endothelial progenitor cells, Lnk and bone fracture healing -- Stromal cell-derived factor 1/CXCR4 signaling, stem cells, and fractures -- Chromatin remodeling and transcriptional control of mesenchymal cells towards the osteogenic pathway -- Use of chondrogenic progenitor cells in osteoarthritis -- Allogenic mesenchymal stem cells for bone tissue engineering: clinical and basic research on perinatal hypophosphatasia -- Haematopoietic stem cell transplantation in autosomal recessive osteopetrosis -- Human fetal stem cells and osteogenesis imperfecta: rodent studies -- G-CSF-mobilized haploidentical peripheral blood stem cell transplantation in childhood osteopetrosis -- Combining osteochondral stem cells and biodegradable hydrogels for bone regeneration -- Rabbit adipose-derived stem cells and tibia repair -- Transplantation of human adipose-derived stem cells for fracture healing: multi-lineage differentiation potential and paracrine effects 
520 |a Preface Bone diseases, characterised by either fractures, stunting, loss of mineral composition or strength, are important causes of morbidity and mortality. For example worldwide there are 9 million new cases of fractures due to osteoporosis annually and this has increased by 50% in the past 2 decades. As the population ages, these fi gures will further increase, imposing burdens on individuals, communities, and health providers. As a result, new treatments and strategies are continually being developed to prevent bone diseases occurring and also to treat such conditions. Stem cells potentially offer a novel therapeutic platform to treat bone disease. They also help the scientist understand the molecular and cellular aetiology of bone disorders. Gaining knowledge on the nature and application of stem cell sciences is a prerequisite for understanding their potential in treating or preventing bone disorders. However, obtaining information on stem cells per se and their usage and applications in treating skeletal disorders is currently problematic, as such text-based material is either sporadic or directed towards the expert. This book Stem Cells and Bone Tissue is designed to address such limitations. It is multidisciplinary and covers all scientifi c levels. Stem Cells and Bone Tissue has three major sections: Section 1: Introductory Text and Sources of Stem Cells for Skeletal Tissue Section 2: Cellular and Molecular Aspects Section 3: Conditions, Applications, Treatments and Repairs The simplistic nature of the main section headings, however, should not detract from the fact that individual chapters are highly detailed. Coverage includes for example, general aspects of stems cells, sources of stems cells, isolation and purifi cation, applications in. 
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650 0 |a Stem cells 
650 0 |a Bones  |x Metabolism  |x Disorders 
650 1 2 |a Bone Diseases  |x therapy 
650 2 2 |a Stem Cells 
700 1 |a Rajendram, Rajkumar  |e editor 
700 1 |a Preedy, Victor R.  |e editor 
700 1 |a Patel, Vinood B.  |e editor 
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