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Micro-and nanoelectromechanical biosensors

In this book, the authors have deliberately decided to break away from the conventional way of treating biosensing research by uniquely addressing biomolecule immobilization methods on a solid surface, fluidics issues and biosensing-related transduction techniques, rather than focusing simply on the...

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Bibliographic Details
Main Authors: Nicu, Liviu (Author), Leichlé, Thierry (Author)
Format: Book
Language:English
Published: London, UK ISTE © 2014
Series:Focus nanoscience and nanotechnology series
Subjects:
Biosensors
Nanotechnology
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Table of Contents:
  • CHAPTER 1. TRANSDUCTION TECHNIQUES FOR MINIATURIZED BIOSENSORS 1-- 1.1. Definition of bioMEMS
  • 1.2. Transduction techniques-- 1.2.1. Optical transduction
  • 1.2.2. Electro (chemical) transduction
  • 1.2.3. Mechanical transduction
  • 1.3. MEMS transducers
  • 1.4. One specific application of MEMS biosensors: detection of pathogen agents
  • CHAPTER 2. BIORECEPTORS AND GRAFTING METHODS
  • 2.1. Types of bioreceptor
  • 2.1.1. Catalytic receptors
  • 2.1.2. Affinity receptors
  • 2.1.3. Nucleic acid-based receptors
  • 2.1.4. Molecularly imprinted polymers
  • 2.2. Immobilization strategies
  • 2.2.1. Adsorption and antifouling strategies
  • 2.2.2. Entrapment methods
  • 2.2.3. Covalent coupling
  • 2.2.4. Other capture systems
  • 2.2.5. Immobilization strategies: summary
  • 2.3. Conclusion
  • CHAPTER 3. PATTERNING TECHNIQUES FOR THE BIOFUNCTIONALIZATION OF MEMS
  • 3.1. What is surface patterning?
  • 3.2. Direct biopatterning in liquid phase
  • 3.2.1. Ink delivery by non-contact methods
  • 3.2.2. Ink delivery by contact methods
  • 3.3. Replication of patterns
  • 3.3.1. Photolithography
  • 3.3.2. Light-induced patterning strategies
  • 3.3.3. Microcontact printing
  • 3.3.4. In-flux functionalization
  • 3.4. Conclusions
  • CHAPTER 4. FROM MEMS TO NEMS BIOSENSORS
  • 4.1. Importance of downscaling
  • 4.2. Challenges faced by NEMS for biosensing applications
  • 4.2.1. Issues related to nanomechanical transducers
  • 4.2.2. Issues related to the functionalization of NEMS
  • 4.2.3. On the importance of packaging and sample preparation
  • 4.3. Economic considerations
  • CHAPTER 5. COMPARING PERFORMANCES OF BIOSENSORS: IMPOSSIBLE MISSION?

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