Simulating enzyme reactivity

Table of Contents: “…Perspective on Computer Modelling of Enzymatic Reactions; Fundamentals of Enzymatic Catalysis: Determination of Rate Constants; A Transition State Theory Perspective for Enzymatic Reactions: Fundamentals and Applications; Electron Transfer Reactions in Enzymes: Seven Things that Might Break Down in Vanilla Marcus Theory and How to Fix Them if They Do; Kinetic Isotope Effects; Free Energy Calculation Methods and Rare Event Sampling Techniques for Biomolecular Simulations; Methods to Trace Conformational Transitions; Key Concepts and Applications of ONIOM Methods; First Principles Methods in Biology: From Continuum Models to Hybrid Ab initio Quantum Mechanics/Molecular Mechanics; Nuclear Quantum Effects in Enzymatic Reactions; QM/MM Methods for Simulating Enzyme Reactions; Ribozymes; Effects of Water and Non-aqueous Solvents on Enzyme Activity; Modelling Reactivity in Metalloproteins: Hydrogen Peroxide Decomposition by Haem Enzymes; Enzyme Design…”

The organic chemistry of enzyme-catalyzed reactions by Silverman

Subjects: “…Enzymes…”

Biology by Chia, Lok Thye, Jacqueline R.S, Nalini B.

Table of Contents: “…1.Biological molecules -- 2.Structure of cells and organelles -- 3.Membrane structure and transport -- 4.Enzymes -- 5.Cellular respiration -- 6.Photosynthesis…”

Harper's illustrated biochemistry

Table of Contents: “…Structures & functions of proteins & enzymes -- Bioenergetics & the metabolism of carbohydrates -- Metabolism of proteins & amino acids -- Structure, function, & replication of informational macromolecules -- Biochemistry of extracellular & intracellular communication -- Special topics.…”

Harper's illustrated biochemistry

Table of Contents: “…Biochemistry & medicine -- Water & pH -- Amino acids & peptides -- Proteins: determination of primary structure -- Proteins: higher orders of structure -- Proteins: myoglobin & hemoglobin -- Enzymes: mechanism of action -- Enzymes: kinetics -- Enzymes: regulation of activities -- Bioinformatics & computational biology -- Bioenergetics: the role of ATP -- Biologic oxidation -- The respiratory chain & oxidative phosphorylation -- Carbohydrates of physiologic significance -- Lipids of physiologic significance -- Overview of metabolisms & the provision of metabolic fuels -- The citric acid cycle: the catabolism of acetyl-CoA -- Glycolysis & the oxidation of pyruvate -- Metabolism of glycogen -- Gluconeogenesis & the control of blood glucose -- The pentose phosphate pathway & other pathways of hexose metabolism -- Oxidation of fatty acids: ketogenesis -- Biosynthesis of fatty acids & eicosanoids -- Metabolism of acylglycerols & sphingolipids -- Lipid transport & storage -- Cholesterol synthesis, transport, & excretion -- Biosynthesis of the nutritionally nonessential amino acids -- Catabolism of proteins & of amino acid nitrogen -- Catabolism of the carbon skeletons of amino acids -- Conversation of amino acids to specialized products -- Porphyrins & bile pigments -- Nucleotides -- Metabolism of purine & pyrimidine nucleotides -- Nucleic acid structure & function -- DNA organization, replication, & repair -- RNA synthesis, processing, & modification -- Protein synthesis & the genetic code -- Regulation of gene expression -- Molecular genetics, recombinant DNA, & genomic technology -- Membranes: structure & function -- The diversity of the endocrine system -- Hormone action & signal transduction -- Nutrition, digestion, & absorption -- Micronutrients: vitamins & minerals -- Free radicals and antioxidant nutrients -- Intracellular traffic & sorting of proteins -- Glycoproteins -- The extracellular matrix -- Muscle & the cytoskeleton -- Plasma proteins & immunoglobulins -- Hemostasis & thrombosis -- Red & white blood cells -- Metabolism of xenobiotics -- Biochemical case histories…”

Foye's principles of medicinal chemistry

Table of Contents: “…Part 1: Principles of drug discovery -- Part 2: Drug receptors affecting neurotransmission and enzymes as catalytic receptors -- Part 3: Pharmacodynamic agents -- Part 4: Disease state management…”

Biology term 1 by Richard, Y.K, David Tan

Table of Contents: “…Chapter 1:Biological molecules -- Chapter 2:Structure of cells and organelles -- Chapter 3:Membrane structure and transport -- Chapter 4:Enzymes -- Chapter 5:Cellular respiration -- Chapter 6:Photosynthesis…”

Medical sciences at a glance

Table of Contents: “…Functions6: Carbohydrate biochemistry; Carbohydrate structure; Glucose; Polysaccharides; Glycogen; Structural carbohydrates; 7: Basic mechanisms of drug action; Pharmacological targets; Receptors; Drug-receptor interactions; Description of drug actions -- Part 2: Cellular metabolism; 8: General principles of cellular metabolism; Energy requirements; High-energy phosphates; Enzymes and regulation (Chapter 9); 9: Enzymes; Enzyme kinetics; Michaelis-Menten kinetics; Enzyme inhibition; Key enzymic activities; 10: Central metabolic pathways; The Link Reaction -- pyruvate dehydrogenase; The TCA cycle. …”

Stahl's essential psychopharmacology neuroscientific basis and practical application by Stahl, Stephen M. 1951-

Table of Contents: “…Chemical neurotransmission -- Transporters, receptors and enzymes as targets of psychopharmacological drug action -- Ion channels as targets of psychopharmacological drug action -- Psychosis and schizophrenia -- Antipsychotic agents -- Mood disorders -- Antidepressants -- Mood stabilizers -- Anxiety disorders and anxiolytics -- Chronic pain and its treatment -- Disorders of sleep and wakefulness and their treatment -- Attention deficit hyperactivity disorder and its treatment -- Dementia and its treatment -- Impulsivity, compulsivity and addiction…”

Clinical Chemistry / by Marshall, William J., Lapsley, Marta, Day, Andrew P., Shipman, Kate

Table of Contents: “…An Introduction to Biochemistry and Cell Biology -- Biochemical Investigations in Clinical Medicine -- Water, Sodium and Potassium -- Hydrogen Ion Homoeostasis and Blood Gases -- The Kidneys -- The Liver -- The Gastrointestinal Tract -- Clinical Nutrition -- The Hypothalamus and the Pituitary Gland -- The Adrenal Glands -- The Thyroid Gland -- The Gonads -- Disorders of Carbohydrate Metabolism -- Calcium, Phosphate and Magnesium -- Bones and Joints -- Plasma Proteins and Enzymes -- Lipids, Lipoproteins and Cardiovascular Disease -- Muscles, Nerves and Psychiatric Disorders -- Inherited Metabolic Diseases -- Metabolic Aspects of Malignant Disease -- Therapeutic Drug Monitoring and Chemical Aspects of Toxicology -- Clinical Chemistry in Children.…”

Petroleum catalysis in nontechnical language by Magee, John S.

Bioethanol and natural resources substrates, chemistry and engineered systems by Ceballos, Ruben Michael

Lippincott's illustrated reviews by Champe, Pamela C.

Table of Contents: “…Amino acids ; Structure of proteins ; Globular proteins ; Fibrous proteins ; Enzymes -- Unit II: Intermediary metabolism. Bioenergetics and oxidative phosphorylation ; Introduction to carbohydrates ; Glycolysis ; Tricarboxylic acid cycle ; Gluconeogenesis ; Glycogen metabolism ; Metabolism of monosaccharides and disaccharides ; Pentose phosphate pathway and NADPH ; Glycosaminoglycans and glycoproteins -- Unit III: Lipid metabolism. …”

Biohazard the chilling true story of the largest covert biological weapons program in the world, told from the inside by the man who ran it by Alibek, Ken

Table of Contents: “…Military medicine -- 4. The enzyme project -- Biohazard. 5. Lab work -- 6. Building 107 -- 7. …”

Introduction to chemical reaction engineering and kinetics by Missen, Ronald W. (Ronald William) 1928-

Table of Contents: “…. -- Biochemical Reactions: Enzyme Kinetics. Preliminary Considerations in Chemical Reaction Engineering. -- Batch Reactors. -- Ideal Flow. …”

Drug stereochemistry analytical methods and pharmacology

Body foods for life feel good, look good, stay good by Clarke, Jane

Table of Contents: “…Part 4 Stay good: preventing and managing health problems; pregnancy; ageing (senile dementia, Alzheimer's); anaemia; MS; arthritis and gout; diabetes (childhood and adult); high blood fats; high blood pressure; heart disease; cancer; raised liver enzymes (men); Parkinson's disease. Part 5 Taste good: 100 recipes.…”

Biochemistry concepts and connections by Appling, Dean Ramsay, Anthony-Cahill, Spencer J., Mathews, Christopher K., 1937-

Table of Contents: “…Protein Function and Evolution 8. Enzymes: Biological Catalysts 9. Carbohydrates: Sugars, Saccharides, Glycans 10. …”

Medical Biochemistry by Baynes, John W., Dominiczak, Marek H.

Table of Contents: “…Introduction -- Amino acids and proteins -- Carbohydrates and lipids -- Blood: cells and plasma proteins -- Oxygen transport -- Catalytic proteins enzymes -- Hemostasis and thrombosis -- Membranes and transport -- Bioenergetics and oxidative metabolism -- Function of the gastrointestinal tract -- Micronutrients: vitamins and minerals -- Anaerobic metabolism of glucose in the red blood cell -- Carbohydrate storage and synthesis in liver and muscle -- The tricarboxylic acid cycle -- Oxidative metabolism of lipids in liver and muscle -- Biosynthesis and storage of fatty acids -- Biosynthesis of cholesterol and steroids -- Lipoproteins and lipid transport -- Biosynthesis and degradation of amino acids -- Muscle: energy metabolism and contraction -- Glucose homeostasis and fuel metabolism -- Nutrition and energy balance -- Water and electrolyte homeostasis -- Regulation of hydrogen ion concentration (acid-base balance) -- Calcium and bone metabolism -- Complex carbohydrates: glycoproteins -- Complex lipids -- The extracellular matrix -- Role of the liver in metabolism -- Biosynthesis and degradation of nucleotides -- Deoxyribonucleic acid -- Ribonucleic acid -- Protein synthesis and turnover -- Regulation of gene expression -- Recombinant DNA technology -- Genomics, proteomics and metabolomics -- Oxygen and life -- The immune response -- Biochemical endocrinology -- Membrane receptors and signal transduction -- Neurochemistry -- Neurotransmitters -- Cellular homeostasis: cell growth, differentiation and cancer -- Aging.…”

Drugs for the heart

Table of Contents: “…Kaplan -- Inhibitors of angiotensin-converting enzyme, angiotensin II receptor, aldosterone, and renin / Lionel H. …”